I've had the lip lush for over a month luv it.59 y/o & a smoker.I have liplines/creases& a thin upper lip.I put the lip lush on and above the top lip. a/m/ & p.m. My lips seem to swell up just enough that the line/creases are gone and my thin upper lip is slightly enlarged.. and there is a risidual effect,since on weekends or when I go for several days not using it, the line/creases are still greatly lessened. I am very white/fair skined.Using other 'Derma" Products w sucess also.